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Sometimes its due to an underlying health issue, while other times it might be a side effect of medication or a result of lifestyle factors

Cost and risk follow the same curve

Brown SR, Baraza W, Din S, Riley S (2016) Chromoscopy versus conventional endoscopy for the detection of polyps in the colon and rectum

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Classical tachykinins (SP, NKA and NKB) possess a wide distribution in the central and peripheral nervous system, which is one of the major sources of these peptides [116]