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The most commonly reported side effects include: Nausea Diarrhoea Vomiting Mild stomach discomfort Constipation In TRIUMPH-1, treatment discontinuation due to adverse events rose with dose: approximately 4.1% at 4 mg, 6.9% at 9 mg, and 11.3% at 12 mg , compared with 4.9% in the placebo group

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Stool softeners like docusate sodium have limited evidence supporting their efficacy as monotherapy but may be combined with other laxatives