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Eligibility is limited to legitimate clinical-trial criteria until regulators approve an indication

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The gastrointestinal side effects are consistent with GLP-1 receptor activation and are generally manageable with appropriate dosing strategies and patient education

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Tirzepatide (Zepbound) for the treatment of obesity

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These effects are part of why treatment may help some patients feel full sooner and reduce food noise

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Efficacy: Semaglutide has superior reductions in HbA1c and body weight compared to other agents, while tirzepatide, a dual GLP-1/GIP receptor agonist, shows even greater efficacy but with higher rates of adverse events

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