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It disrupted mitochondrial integrity and impaired antioxidant defenses via the Nrf2/Gpx4 pathway

In 1969 as the fortunes of the company and Okinawa improved, the name was changed to Helios and over the next two decades it branched out and gained licenses to make sake, shch, awamori (an Okinawan local spirit made from rice), whiskey and, in 1996, beer, which became one of its primary products with amawori and for which it is now best known

Not Manufactured With Wheat, Gluten, Soy, Milk, Egg, Fish, Shellfish Or Tree Nut Ingredients