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Rotating injection sites and proper technique minimize this risk

References [1] EASO Update Gives Clearer Roles to Tirzepatide and Semaglutide [2] PMC13143735 [3] Semaglutide vs Tirzepatide ACC Journal Scan [4] Tirzepatide vs Semaglutide Real-World Obesity Study [5] PMC11970626 [6] PMC12151102 [10] PubMed 40353578

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The most common are gastrointestinal: nausea, constipation, diarrhea, and reflux, usually early on or after a dose increase