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Anti-inflammatory, alleviation of diabetes-induced oxidative stress, and increased hepatic glycogen synthesis mechanisms have also received attention (Zhou 2022

These factors can significantly influence effectiveness

Within the context of PCOS, GPER not only influences the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) by regulating the function of the hypothalamicpituitaryovarian (HPO) axis but also improves ovarian function, reduces androgen levels, and promotes normal follicular development and ovulation [156]

Every patients protocol is different, but this is the framework we use at YoungerMeMD to guide treatment decisions

However, itemized analysis revealed that THC augmentation specifically improved gastrointestinal symptoms (U = 16.00, p = 0.025) compared to ESC monotherapy, while showing marginally significant lesser improvement in psychomotor agitation (p = 0.053)