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Plasmodium falciparum in vitro continuous culture conditions: A comparison of parasite susceptibility and tolerance to anti-malarial drugs throughout the asexual intra-erythrocytic life cycle

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The Endocrine Society's 2015 obesity pharmacotherapy guidelines recommend that "dose escalation be delayed for patients experiencing intolerable adverse events." This applies directly to GLP-1 agents and gives prescribers explicit guideline backing to slow the titration schedule when needed [12]

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Post-discontinuation success depends on how well these behaviors persist