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Yes, many patients with pre-existing depression use semaglutide successfully

Here, we repurpose the native IgG FcFcR interaction into a universal, covalent docking site using only a single engineered disulfide bond, providing a simple solution to bypass the complex, bespoke engineering typically required for multispecific antibody design

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Additionally, the central and peripheral nervous pathways activated by GLP-1 are independent and synergistic