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NAD+ levels decline with age and metabolic dysfunction, and restoring them through supplementation has shown promise in animal models for improving insulin sensitivity, enhancing mitochondrial biogenesis, and promoting fat oxidation

Glucagon-like peptide 1 (GLP-1) receptor agonist: The gastrointestinal tract releases GLP-1, a major incretin, in response to glucose consumption

Adding another layer of complexity, a multinational survey revealed that only 26% of clinicians viewed obesity as a chronic disease, and fewer than half routinely recorded it as such in patients medical files (Dixon et al., 2025)

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[4] Lack of a postictal period