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Furthermore, there were significant differences in the mRNA expression levels of the chondrogenic markers COL2A1, SOX9, and ACAN , with a greater increase in GSH-high hES-MSCs compared to the other two groups (Fig

Plasma levels of hepatotoxic makers such as aspartate aminotransferase (AST) and alanine aminotransferase (ALT), as well as albumin concentration, were comparable among tested groups, indicating no significant safety concerns, despite the higher occurrence of knockout over knock-in events (Fig

It is an important tri-peptide that contains cysteine, glutamic acid, and glycine

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