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A clinical trial of glutathione supplementation in autism spectrum disorders Janet K Kern, David A Geier, Published December, 2011 in Medical Science Monitor The results suggest that oral

However, some patients receiving high-dose B12 supplementation or injections may experience adverse reactions, though these relate to the treatment rather than the elevated levels: Possible reactions to B12 supplementation (particularly injections): Skin reactions, including acneiform eruptions or rashes Pruritus (itching) Injection site reactions (with parenteral administration) Rare hypersensitivity reactions Non-specific symptoms such as headaches, dizziness, or gastrointestinal disturbances have been reported by some patients taking B12 supplements, but causality is not well established in clinical evidence

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Antioxidants (Basel) 2020;9(12):1283

& Huang, Y-L