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Research is advancing to evaluate retatrutides comparative efficacy, pharmacological profile, and positioning relative to other emerging options

Kay Lund were postdoctoral researchers working in Joel Habener's laboratory at Massachusetts General Hospital

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We found that co-administration of nifedipine, an inhibitor of V-gated Ca 2+ -channels, almost completely abolished the response to l-valine, indicating that l-valine induced GLP-1 secretion is dependent on activation of voltage-gated Ca 2+ -channels