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Extended dosing intervals may create a false economy: you might feel like you are 'stretching' your supply, but you may also sacrifice the appetite control that makes a weight loss program stick

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While individual ingredients like berberine have known safety profiles when taken orally, their safety when delivered through skin patches hasnt been established

Not everybody responds the same way to the treatment and individual results will vary

10.1038/cr.2010.165 Cell Res