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Senescence induction in colon (HTC116) and bladder (EJ) cancer cell lines, followed by an incubation with the B2M-ADC, led to the clearance of 35% of senescent cells
Severe histological alterations, including germinal cell dissociation and atrophied seminiferous tubules, were observed in T1DM rats
Females resilient to trauma exhibited higher pre-trauma levels of Roseburia, Oscillibacter , and Lachnospiraceae , suggesting that baseline enrichment of SCFA-producing bacteria may confer resistance to PTSD onset (Tanelian et al., 2023)
Our NAC regimen proved safe, with minimal, mostly gastrointestinal side effects