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Despite decades of clinical reliance on nucleoside analogues such as acyclovir, the therapeutic landscape has stagnated with rising antiviral resistance, toxicity associated with prolonged use, and the complete inability of current drugs to eliminate latency or prevent reactivation continue to undermine effective disease control

Tsai JP, Yang FL, Wang CH, Fang TC, Lee RP, Hsu BG

DOI: 10.1097/NEN.0b013e3181cb5af4.Oxidative 84