2 Dopaminergic neurotransmission in PD pathogenesis The dopaminergic neurotransmission in PD pathogenesis involves the loss and apoptosis of dopaminergic neurons in the brain, as well as a reduction in dopamine levels, leading to an absolute deficiency of dopamine (15)
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Although mitochondrial respiration was noted as unchanged in resting and stimulated CD4+ and CD8+ T cells, CD8+ T cells were found to have a reduction in proton leak, ATP synthesis, and mitochondrial membrane potential (254)
