Muscle Nerve 34, 789793
Over time, its applications expanded from wound healing research into dermatology, cosmetic formulations, hair restoration, and emerging regenerative medicine
In vitro studies show GHK-Cu protecting retinal pigment epithelial cells from oxidative stress and UV damage
Trends Pharmacol Sci 35(3):146154 Hunot S, Brugg B, Ricard D, Michel PP, Muriel MP, Ruberg M, Faucheux BA, Agid Y, Hirsch EC (1997) Nuclear translocation of NF-B is increased in dopaminergic neurons of patients with Parkinson disease
By targeting the GHR to the nucleus by fusing a nuclear localization signal to the receptor, it was found in the absence of GH that several genes known to be involved in oncogenesis were upregulated, and further studies provided evidence that the GHR can bind to a transcriptional regulator (299, 302)