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Metabolomics has facilitated the discovery of novel circulating biomarkers, while scRNA-seq has illuminated kidney cellular heterogeneity, mapped intercellular communication networks, and uncovered previously unrecognized disease-associated cell states (Wu et al., 2022a

IV fluids restore fluid balance and electrolytes faster than oral fluids

Prevents free radical damage

Neither has a pharmaceutical formulation, standardized purity requirements, or GMP manufacturing standards commonly applied to approved drugs