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npj Metab Health Dis 3 , 16 (2025)

Semi-quantitative histopathological assessments were performed for cardiac tissue as well as for potential congestion in the liver, kidneys, and bronchial mucosa

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Hyperglycemic state increases the production of di-lipoylglycerol (DAG) (Hayashi and Shirai, 2022), which is an endogenous activator of PKC