Guidance on specific medications is below: Semaglutide: Useful unrefrigerated for 3 days, up to 90 degrees F
It is approved for: Adults with obesity (BMI 30) Adults who are overweight (BMI 27) with related conditions Children ages 12 and older with obesity Wegovy is used alongside a reduced-calorie diet and increased physical activity
The investigation specifically showed that these drugs did not increase the risk of any fractures, confirming their safety profile in clinical practice (72)
Weight Loss: The Data At this time, there arent any published head-to-head obesity trials directly comparing oral semaglutide to orforglipron, says Maria Teresa Anton, MD, a board-certified internal medicine physician who specializes in endocrinology, diabetes, and metabolism with Pritikin Longevity Center in Miami
The study reviewed posts from approximately 70,000 users over several years