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OuXYangHRamaniKAraAIChenHMatoJMet alInhibition of human betaine-homocysteine methyltransferase expression by S-adenosylmethionine and methylthioadenosine

Alpha lipoic acid ameliorates motor deficits by inhibiting ferroptosis in Parkinsons disease

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Traditional treatments (topical steroids, biologics, immunosuppressants) target these pathways directly

ROS increase the severity of bronchial asthma by activating numerous inflammatory mediators, including leukotrienes B4 (55) and D4, regulated on activation, normal T-cell expressed and secreted (RANTES) chemokines, eotaxins, IL-5 (55), IL-1, -4, -6, GM-CSF, interferon (INF), platelet-activating factor (PAF), tumor necrosis factor (TNFa), adhesion molecules (VCAM-1) (56) and major basic protein (MBP) (57)