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instead, it is concentrated in tissues and cells that are vulnerable to oxidative stress and inflammation, such as the bone marrow, developing red blood cells, monocytes, macrophages, and specific epithelial barriers, while its expression in the central nervous system remains uncertain

Inhibition of preadipocyte proliferation by mitochondrial reactive oxygen species

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They may get little to no B12 from their food, because vitamin B12 only occurs naturally in animal sources