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doi: 10.1016/j.jacc.2013.11.004 24 GarveyWTMechanickJIBrettEMGarberAJHurleyDLJastreboffAMet al

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Since side effects are often linked to dose strength, starting on a lower dose helps the body adjust and can reduce their impact

Indeed, if tirzepatide and other GLP-1 drugs for weight loss become subject to mandatory discounting through the Inflation Reduction Act (by 2031, or sooner if their developers attempt to reduce prices in anticipation of this deadline) or similar regulation, their prices would be directly reduced, making them more affordable

But those taking a GLP-1 for weight loss may think about reducing their dose or even stopping completely once they reach their goal weight