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Medical claims are submitted by providers or facilities for clinical services

The optimal dosing window is 3045 minutes before sleep in a fasted state (minimum 3 hours post-meal, ideally 45 hours)

The timing of oral contraceptive administration in relation to tirzepatide injections may also require adjustment

Continuous variables were assessed using mean difference (MD) and corresponding 95% confidence intervals (CI), while dichotomous variables were assessed using combined odds ratio (OR) and corresponding 95% confidence intervals