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DAMPs released by pyroptotic cells as major contributors and therapeutic targets for CAR-T-related toxicities

(1) FSP1/AIFM2: FSP1 was originally classified as a caspase-independent apoptosis-inducing protein, on the basis of its sequence similarity to apoptosis-inducing factor 1 (AIFM1), and was annotated as a flavoprotein with NAD(P)H oxidase activity 38

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Comparative studies have found GHK-Cu to be as effective as retinol and vitamin c in improving visible signs of aging, but with significantly lower rates of skin irritation

We also tested therapeutic response in less advanced colon lesions, using Vil-Cre