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Federman DG, Froelich CW, Kirshner RS

NUEM Blog

The phrase researchers keep coming back to is "modulate, not suppress." KPV tones down excess signaling rather than disabling the immune response, so the body's normal defenses are meant to stay intact

these were not completed in peer-reviewed form, and a Phase I safety study has been mentioned in the literature but its results were never published

Current research extrapolations suggest 1216 week treatment cycles followed by 48 week rest periods, though this is based on precautionary principle rather than evidence of receptor desensitization or tolerance development