Chen Y, Wang X, Wang J, Yan Z, Luo J
A 2025 systematic review and meta-analysis in Reviews in Endocrine and Metabolic Disorders found that tirzepatide (the active ingredient in Mounjaro and Zepbound) reduced hsCRP by approximately 33% and IL-6 by approximately 18% compared to placebo across patients with and without diabetes. A growing body of research suggests this effect occurs through direct action on the NF-B pathway, a master switch of inflammation
If affordability is a concern, talk to your doctor about: Lower-cost alternatives including older oral medications we keep in stock at the clinic (phentermine, diethylpropion, Contrave, and others) Dose optimization staying on the lowest effective dose Patient assistance programs through the manufacturer Splitting strategies for some injectable pens at higher doses For a broader look at how CNC approaches pricing and insurance: Insurance, Cost & Medication Access
Most are injected subcutaneously (under the skin) once daily or weekly using a simple pen device
Our GLP-1 meal plan is expertly designed to assist your weight loss journey while using GLP-1 medications under your physicians guidance