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Moreover, like other medications in its class, there is a warning regarding the risk of thyroid C-cell tumors, based on animal studies, although its relevance to humans remains under investigation

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The inhibition of the SLC7A5, SLC38A2 and SLC25A22 transporters may inhibit the uptake of glutamine in KRAS-mutant tumor cells, thereby inhibiting the growth and metabolism of tumor cells and achieving therapeutic effects [50]

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