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however, immunohistochemistry (IHC) investigations revealed decreased expression of IGF-1, 8-OHdG, and ARs in both tumor and adjacent normal tissues

The oxidation level and substitution patterns on the C ring determine the flavonoid classes, while individual compounds within each class differ based on the substitution pattern of the A and B rings

Its worth noting that in certain medical protocols, MB has been used to treat ifosfamide-induced encephalopathy and can itself cause self-limited nausea during that treatment regimen

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