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STANDARDS FOR EVALUATING THE EFFICACY OF OBESITY TREATMENT DRUGS The mechanisms of action and structural formulations of GLP-1RA-based therapies for obesity are detailed in Figs

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In elderly and obese subjects, it improves inflammatory blood markers, energy metabolism at bedtime, and fatty liver [181,182,183], though not insulin sensitivity, glucose tolerance, or skeletal muscle mitochondrial function [181,182,184]

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Identifying the causes of stigma and educating the public about the associated consequences may help equip communities with more effective social skills to combat these pervasive and harmful attitudes and ultimately improve prevention and treatment endeavors [31, 32]