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Key Takeaways GLP-1 is your body's natural "I'm full" hormone, and lower levels might contribute to weight gain If you're dealing with perimenopause or postmenopause weight gain, cravings, blood sugar issues, or insulin resistance, extra support can help with achieving and maintaining a healthy weight There's limited evidence that some supplements like fiber, probiotics, and berberine might help boost GLP-1 levels, though they can support weight loss in other more well-researched pathways

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For others, metabolic effects and calorie expenditure may play a larger role

If symptoms persist, Dr