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While niacin supplementation can improve muscle mass and positively impact lipid profiles 15 in mitochondrial disease patients and healthy population, it has been also associated with hyperglycemia 28

In 2020 another open-label RCT of triple therapy with or without NAC, 1200 mg per day, was published, and reported that addition of NAC did not improve eradication rates

Aqueous Phase Chain Breaking Antioxidants: These antioxidants act on radicals present in the aqueous compartment

Publication Date 2019