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Across the STEP clinical trials, patients had a mean age of 46.255.3 years, were mostly female (74.181.0%), and had a mean BMI of 35.738.5 kg/m 2 [22]

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Asthma exacerbations were defined as the need for an oral corticosteroid (OCS) prescription

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Since FCH4 had the highest HCV antigen load in the liver and both isolates were associated with very high serum titers, it appears likely that they still represent high replicators in vivo