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This is consistent with the understanding that obesity is a chronic condition requiring ongoing management
Unlike current GLP-1 receptor agonists such as semaglutide (Ozempic, Wegovy), Retatrutide is a triple hormone receptor agonistactivating GLP-1, GIP, and glucagon receptors simultaneously
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Retatrutide is an investigational triple incretin receptor agonist targeting GLP-1, GIP, and glucagon receptors currently in Phase 3 trials with no global regulatory approval
As DiMarchi points out, 'What you're trying to do is take two individual keys and make a master key that is every bit as effective as the two individual parts.' To their surprise they noticed that mice lost more weight when injected with a balanced dual agonist than when given one more centred on GLP-1
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