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Fissures are usually visible on examination and respond well to conservative measures such as stool softeners, topical treatments, and sitz baths

Methylation of GLUD1 enhances protein stability As arginine methylation plays a crucial role in regulating protein function, we first examined the effect of GLUD1 arginine methylation on protein stability

Exposure to HIV-1 directly impairs mucosal epithelial barrier integrity allowing microbial translocation

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This fundamental difference in metabolism means they do not compete for the same enzymatic pathways, minimising the risk of one medication affecting the blood levels of the other