glp-1 vs glp 2 vs glp 3 GLP-2 GLP-3: The Science Behind Modern Metabolic Peptides Episode 3: GLP-1 vs GLP-2

It activates AMP-activated protein kinase (AMPK), a key metabolic regulator, and influences glucose and lipid metabolism through multiple pathways

Luca G, Parrettini S, Sansone A, Calafiore R, Jannini EA

For instance, semaglutide has been approved and is being researched for indications including obesity, T2DM, reducing cardiovascular risk, chronic kidney disease, NAFLD, and AD, indicating that the development of new indications could provide new growth opportunities for GLP-1 drugs

10.1016/j.obpill.2024.100127 37 GinesP.Serra-BurrielM.KamathP

The ACC recommends GLP-1R agonists for cardiovascular risk reduction in patients with T2DM and established ASCVD [114]