Weve spent the last two years drawing on Nooms deep expertise in behavior change to create the ultimate GLP-1 companion program to solve the medications twin challenges, persistence and muscle-mass loss, while also driving enhanced weight loss outcomes, he details
and $4.4 billion internationally, up from $1.2 billion in Q1 2025
Box 1: Recent Trump Administration Obesity Drug Initiatives In November 2025, the Trump administration announced reaching a deal with Eli Lilly and Novo Nordisk to lower the cost of their GLP-1s for Medicare, Medicaid, and those purchasing the drugs directly from the manufacturers through a new TrumpRx website
Promotion of autophagy mechanism The basic activity level of autophagy in muscle tissue is directly related to the maintenance of muscle health, since autophagy is one of the core protective mechanisms for cells to maintain their own homeostasis
To qualify for Semaglutide GLP-1 injections for weight loss, individuals must meet certain criteria