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Healthcare providers trained to recognize this triad may miss patients with incomplete or evolving symptom patterns

Pedersen, B

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If you take a blood thinner (an anticoagulant or antiplatelet medication such as aspirin, warfarin, Plavix, Eliquis, or Xarelto), tell your provider before starting, because injections can bruise or bleed more easily

As mentioned above, there is some incidence of a phenomenon referred to as a post-injection flare wherein the injection of fluid into the knee stretches the knee capsule and induces an initial inflammatory pain response that can last for a day or so