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The application of semaglutide may reduce the proliferation of SMCS by reducing Coll5a1, reduce the binding to LDL, and delay the development of arterial lesions

Botany 74 (11), 33133327

Patients are "better served" by an expert, such as a weight-loss physician or primary care doctor, who can closely monitor them while taking these drugs, the doctor suggested, especially with the risk of certain side effects, like nausea or pancreatitis

the studies cited below are phase 1b and phase 2 trials