What does the clinical evidence say
Niacinamide (Vitamin B3): A high-purity ingredient that strengthens the skins protective barrier, improves elasticity, and treats discoloration for a more uniform and balanced look
This heightens susceptibility to the toxic effects of iron overload, disrupting intestinal mucosal homeostasis and triggering local inflammation and cell death, ultimately precipitating the onset of gut-associated diseases ( Iron overload-related diseases rank among the most prevalent genetic disorders in humans, characterized pathologically by systemic iron accumulation resulting from excessive dietary iron absorption and iron-induced oxidative stress responses ( 3 Ferroptosis and inflammatory bowel disease The imbalance in ferroptosis regulation plays a key role in the pathogenesis of various diseases
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[DOI] [PubMed] [Google Scholar] 137.Jong C.J., Azuma J., Schaffer S
