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It has biological mechanisms that work against your efforts, and in many cases, those mechanisms require medical intervention to overcome not more discipline, not better supplements, not a stricter diet

Mutations in the neurotrophic factor receptor neurotrophic receptor tyrosine kinase 2 (NTRK2), which affect neuronal survival and synaptic plasticity, contribute to a complex array of phenotypes including obesity, severe intellectual disability, and blunted pain response [8,12]

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Strategies for targeting cancer immunotherapy through modulation of the tumor microenvironment

Some patients receiving GLP-1RAs report that food tastes different, is less enjoyable, or becomes less tempting, yet these experiences are often grouped together as taste changes. This review argues that such reports should be interpreted through a sensorylikingwanting framework rather than as evidence of a uniform gustatory disorder