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A call for caution and for further investigations in these groups of people, including those with pre-existing psychiatric disorders, such as depression, is probably justified. However, Stephen Evans, emeritus professor of pharmacoepidemiology at the London School of Hygiene and Tropical Medicine, said: In my view, this is not a significant or noteworthy paper, and it has major limitations

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The benefits of ketogenic diets described above, for instance, demonstrate the importance of GI microbiota, which is a required intermediary for the effect of these diets in seizure protection (by modulating GABA production or AMPA receptor binding, for instance [128, 129])

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Your liver works hard to process both substances, and combining them puts excessive strain on this vital organ