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Additionally, McConkey et al., in 1967, observed the occurrence of transparent skin that was associated with a decrease in dermal collagen in postmenopausal women [21]

329,330 It has been reported that dehydroabietic acid binding to Keap1 in hydroxide-induced MAFLD mice, promoting the expression of GSH, GPX4, and HO-1, thereby reducing ROS and MDA accumulation

Autologous transplantation of CD34 + hematopoietic stem and progenitor cells transduced with BB305 lentiviral vector encoding beta AT87Q -globin gene was reported to eliminate the need for blood transfusion in 91% of children and adults 50 years old with TDT and nonbeta 0 /beta 0 genotype (185)

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Ongoing surveillance is only recommended if extensive gastric atrophy, intestinal metaplasia, or additional risk factors are identified