Semaglutide injections require accurate placement in the subcutaneous tissue layer beneath the skin to ensure consistent medication absorption
In the Phase II SYNERGY-NASH trial, up to 62% of tirzepatide recipients achieved MASH resolution without worsening of fibrosis, versus 10% in the placebo group, while up to 55% saw improvement of at least one fibrosis stage without worsening of MASH, versus 30% of placebo recipients
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Regarding treatment continuation, the SmPCs provide specific stop rules
I, uh, I went to medical school and then really was on the outside looking in saying, everybody seems to really know what they want, and Im just sort of going to observe things for a while