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However, the NAC monotherapy arm (600 mg three times daily) showed a trend toward slower decline in forced vital capacity (FVC) that did not reach statistical significance compared to placebo (Martinez et al., N Engl J Med, 2014) [45]

The frequency of occurrence and enrichment in visit 3 of specific ABR gene classes for aminoglycosides, beta-lactams and tetracycline was further investigated to follow up the results obtained in Fig

Reported molecular endpoints include VEGFR2 expression and internalisation, FAK and paxillin phosphorylation, growth hormone receptor expression in tendon fibroblasts, and Egr-1 pathway activity

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