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Observational data further suggest that long-term metformin use lowers the risk of myocardial infarction by approximately 33% ( In contrast, evidence in non-diabetic populations remains inconsistent: some studies report improved vascular function and reduced myocardial ischemia in non-diabetic women treated with metformin (Jadhav et al., 2006), whereas the GIPS-III trial showed no improvement in left ventricular ejection fraction after myocardial infarction in non-diabetic patients (Lexis et al., 2014

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Research indicates that the peptide may activate telomerase, the enzyme responsible for maintaining and elongating telomeres

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