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Despite lower systemic absorption, it maintains local activity in the gut , offering significant benefits for: Ulcers and acid damage Leaky gut and intestinal inflammation NSAID-induced GI injury Key features: Shorter systemic half-life (~24 hours) Strong local effect on gastric mucosa Best used for digestive repair and mucosal protection Which Clears Faster

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GLP-1R is expressed in the brainstem nucleus tractus solitarius, in the hypothalamic arcuate nucleus, in the vagus nerve, in the stomach, and in the heart