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If yes, no specific follow up for B 12 is required

(2000) Heffernan, Jiang, Thorburn, and Ng evaluated the metabolic effects of orally administered AOD-9604 in rodent models and the lipolytic activity of the compound on isolated human adipose tissue ex vivo

In a healthy diet, B12 comes from animal products

Animal Studies: Strong Results in Obese Rodent Models The foundational animal work was conducted in obese Zucker rats and ob/ob mice, two standard models for studying obesity