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UC patients show increased ILC1s and ILC2s frequencies but decreased NKp44 + ILC3s, which are crucial for IL-22-mediated epithelial barrier protection [80]

S., Hirsova, P., Maiers, J

The skin-specific mechanisms of GHK-Cu include stimulation of Type I and Type III procollagen synthesis, increased production of dermatan sulfate and other glycosaminoglycans, activation of the enzyme lysyl oxidase (which cross-links newly formed collagen), reduction of matrix metalloproteinase-1 (MMP-1, collagenase) activity, and anti-inflammatory suppression of TNF-alpha-induced IL-6 secretion

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J Nutr (2004) 134(8):19649