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Results Induction of p70S6K1 phosphorylation by IGF-1R inhibitor is independent of K-Ras and PIK3CA mutations Previously, we demonstrated that treatment of HCT116 and SW480 cells with an IGF-1R inhibitor, OSI-906, increases phosphorylation of p70S6K1

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Similar content being viewed by others Log in or create a free account to read this content Gain free access to this article, as well as selected content from this journal and more on nature.com or References Marseglia L, D'Angelo G, Manti S et al , Oxidative stress-mediated aging during the fetal and perinatal periods